If you’re coming from San José, or the central pacific region,you can come through san ramon:
Panamerican Highway, Route 1: If you are driving, set your Google Maps or Waze in San Ramon.
You will pass through the town of San Ramón, and ascend to the Los Ángeles cloud forests; then you will notice that the route starts descending.
Then you will reach La Tigra, and a little further, and right before the Peñas Blancas River, the road divides.
The most picturesque and convenient is the one taking the Peñas Blancas River Bridge.
The alternate route will take you past Tanque town and on to La Fortuna, it is less winding, but it will take a bit longer.